مريضة بدأت لاموتريجين لثنائي القطب قبل ٣ أسابيع، ظهر عندها طفح جلدي منتشر مع حرارة وتقرحات في الفم. ما الإجراء؟

A woman started lamotrigine for bipolar disorder 3 weeks ago and now has a widespread rash with fever and mouth ulcers. What is the action?

1. Apply a cream and review in a week
2. Give an antihistamine and continue
3. Stop the drug and notify the provider at once
4. Double the dose to overcome the allergy

Answer: C) Stop the drug and notify the provider at once. Rash with fever and mucosal ulcers may be Stevens–Johnson syndrome, which is serious; the drug is stopped immediately.