خديج عمره ٥ أيام عنده نفخة مستمرة تشبه صوت الآلة، ونبض قوي جداً، وفرق ضغط واسع. أي دواء قد يُستخدم لإغلاق المشكلة؟

A 5-day-old preterm infant has a continuous machinery murmur, bounding pulses and a wide pulse pressure. Which drug may be used to close the defect?

1. Indomethacin or ibuprofen
2. Prostaglandin E1 infusion
3. A rapid adenosine push
4. Slow IV digoxin

Answer: A) Indomethacin or ibuprofen. This is patent ductus arteriosus. Prostaglandin inhibitors such as indomethacin or ibuprofen help close it in preterm infants. Prostaglandin E1 keeps it open in certain duct-dependent defects.