امرأة عمرها ٢٨ سنة شُخصت بسل رئوي، وبدأت العلاج الرباعي ومنه الريفامبيسين. متزوجة وتستخدم حبوب منع الحمل، وتلبس عدسات لاصقة. وظائف الكبد طبيعية. أي معلومة مهمة في التعليم؟

A 28-year-old married woman diagnosed with pulmonary TB starts four-drug therapy including rifampicin. She uses the combined pill and wears soft contact lenses. Liver function is normal. Which teaching point is important?

1. Green urine means toxicity and the drug must stop at once
2. Take the drug only when coughing
3. The drug strengthens hormonal contraceptives
4. Fluids may turn orange and the pill may fail

Answer: D) Fluids may turn orange and the pill may fail. Rifampicin colours body fluids orange and can stain soft contact lenses, and it reduces hormonal contraceptive efficacy, so another method is needed. It can also affect the liver.