مريض صرع بدأ لاموتريجين قبل ٣ أسابيع، وظهر عنده طفح جلدي. ما التصرف الصحيح؟

Three weeks after starting lamotrigine for epilepsy a client develops a rash. What is correct?

1. Continue, because rash is common and unimportant
2. Double the dose to speed up tolerance
3. Notify the prescriber at once, as the rash may be serious
4. Apply a moisturiser only and continue the drug

Answer: C) Notify the prescriber at once, as the rash may be serious. Lamotrigine can cause serious rashes such as SJS, especially early, with rapid titration or with valproate. Any rash is reported immediately, and doses are increased slowly.