امرأة عندها نزيف دورة غزير منذ البلوغ، ونزيف أنف متكرر، ونزفت كثيراً بعد خلع ضرس. أمها عندها نفس المشكلة. ما الأرجح؟

A woman has had heavy periods since puberty, frequent nosebleeds and heavy bleeding after a dental extraction; her mother has the same. What is most likely?

1. Von Willebrand disease
2. Thalassaemia major
3. B12 deficiency anaemia
4. Haemophilia A

Answer: A) Von Willebrand disease. The commonest inherited bleeding disorder affects both sexes with mucosal bleeding, treated with desmopressin or factor concentrate and tranexamic acid.