زوجان أقارب لديهما طفل مصاب بالتليف الكيسي، ويسألان عن احتمال إصابة الحمل القادم. ما الإجابة الصحيحة؟

A consanguineous couple has a child with cystic fibrosis and asks the risk for the next pregnancy. What is the correct answer?

1. 25% each pregnancy, as it is autosomal recessive
2. Zero, because the first child took the disease
3. 100%, because the parents are related
4. 50% each pregnancy, as it is dominant

Answer: A) 25% each pregnancy, as it is autosomal recessive. With both parents carriers of a recessive gene, each pregnancy has a 25% chance of an affected child and 50% of a carrier. Consanguinity raises the chance of matching recessive genes, so genetic counselling is advised.